Comparative efficacy of pradofloxacin and amoxicillin/clavulanic acid
The predominant bacteria isolated from the oropharyngeal swabs were Pasteurella spp. (26.3 %), E. coli (18.2 %), Staphylococcus intermedius (9.1 %), Streptococcus spp. (7.3 %), Pseudomonas spp. (7.3 %), and other Staphylococcus spp. (4.7 %).
Cats were treated with pradofloxacin 2.5 % oral suspension at a dose rate of 5 mg/kg once daily for five consecutive days, and with amoxicillin/clavulanic acid (Synulox®) at 12.5 mg/kg bodyweight twice daily for five consecutive days.
The mean general condition score of the patients improved significantly within both treatment groups. The rate of pathogen elimination was significantly higher in the pradofloxacin group as compared to the amoxicillin/clavulanic acid group (p < 0.001). The bacterial pathogen was eliminated in almost all cats treated with Veraflox®, while 20% of cats treated with Synulox® were still positive for the causative agent at the end of treatment.