MPC data of pradofloxacin

back

Veraflox® combines high therapeutic efficacy with a high potential of restricting the selection of bacterial resistance under field conditions. MPC90 for pradofloxacin were derived from clinical isolates each of E. coli and S. intermedius 33.

Comparative MIC and MPC rates against E. coli and S. intermedius

Compound

Escherichia coli

Staphylococcus intermedius

MIC90 (µg/ml)

MPC90 (µg/ml)

MIC90 (µg/ml)

MPC90(µg/ml)

pradofloxacin

0.015

0.23

0.06

0.33

enrofloxacin

0.03

0.35

0.12

2.5

marbofloxacin

0.03

0.35

0.25

2.5



The MPCs of the two most active other fluoroquinolones currently available, marbofloxacin and enrofloxacin, were about 1.5-fold higher for E. coli, and 7.5-fold higher for S. intermedius. Veraflox® has the highest potential to restrict selection for resistance in key veterinary organisms compared with other veterinary fluoroquinolones, as demonstrated by its low MIC and MPC values.

Rate this page

latest documents

3rd row with links